LIS Technologies Launches $1.4 Billion Laser Uranium Enrichment Project In Tennessee

LIS Technologies announced a $1.4 billion uranium enrichment project in Oakridge, Tennessee at the former iconic K-25 site, which until 1987 was a massive gaseous diffusion facility built for the Manhattan Project to enrich uranium-235 for atomic bombs. The company will set up shop on the 206-acre on Duct Island, which will be renamed to LIST Island.

Following the renaming of the 206-acre Duct Island to LIST Island and its redevelopment to house the Company’s commercial laser-based uranium enrichment headquarters, Oak Ridge, TN is expected to become the site of the world’s first US-origin commercial laser uranium enrichment facility, supporting U.S. utilities, next-generation reactor developers, and national defense requirements while helping to reestablish a resilient domestic nuclear fuel supply chain.

“Tennessee continues to lead the nation in advancing American energy independence, which is why innovative companies like LIS Technologies recognize our efforts through projects like this,” said Tennessee Governor Bill Lee. “By creating the Nuclear Energy Fund, we have uniquely positioned our state at the forefront of cutting-edge R&D, and I look forward to the positive impact this project will have for Tennesseans across our state.”

The company intends to break ground and begin site preparation and civil construction in 2026 subject to licensing, permitting, and final investment decisions.

LIST is targeting initial commercial operations before 2030, positioning its laser enrichment facility to meet accelerating demand for domestically sourced uranium enrichment.

LIST has partnered with Nano Nuclear to vertically integrate the nuclear fuel chain with reactor development and deployment. The companies are working together to commercialize the Kronos, Zeus, and Loki reactors and supply the necessary fuel for them to operate.

As the push for US nuclear development goes into high gear, the 3rd-generation laser enrichment technology from LIST could be used to produce low enriched uranium (LEU) and high-assay LEU (HALEU) for use in both traditional commercial reactors and advanced reactors throughout the US. The Department of Energy is pursuing the revitalization of the nuclear supply chain due to a current heavy reliance on foreign imports to fuel the nation’s reactor fleet. LIST’s major advantage over its peers in the laser enrichment field is that its process is the only US-origin technology in development. 

LIST states they will pursue site characterization and the initial phases of construction during this calendar year. It is then anticipated the company will begin discussions with the NRC to submit an application for the new nuclear fuel facility.

Nano Nuclear, a developer of small modular reactors, first invested in LIST in 2024, which included an enriched uranium supply agreement between the two companies and a potential for future collaboration on fuel fabrication facilities. Nano is still exploring the potential for entering the fabrication market, but has yet to make any announcements regarding land acquisition or regulatory engagement.

Nano recently entered into an engineering agreement with Ameresco for eventual commercialization of their reactor designs, and most recently started the process for preparing the Loki design for use in space applications. Nano Nuclear acquired the Kronos and Loki designs from the now-defunct Ultra Safe Nuclear Corp during bankruptcy proceedings at the end of 2024.

Nano claims the Kronos design is in a high technical readiness state and is one of the leading high-temperature gas-cooled reactor designs in development. It is expected to enter commercial production by the end of the decade.